Kazia Therapeutics Limited (NASDAQ: KZIA; ASX: KZA), a late-stage, oncology-focused drug development company, marks 'DIPG Awareness Day' by recognizing the tireless work of global researchers in this disease, and by calling for an increased focus on childhood brain cancer among policymakers.
Brain tumours represent the second most common group of cancers in children worldwide, after leukemia, but are the most common cause of cancer death. Around 10-15% of childhood brain cancers are diffuse midline gliomas (DMGs), a group that includes diffuse intrinsic pontine glioma (DIPG).
DIPG most commonly affects children between four and eleven years of age. There is currently no FDA-approved therapy for the disease, and median survival is just 9 – 11 months from diagnosis.
Kazia's paxalisib is the subject on an ongoing phase II study in DIPG and DMGs (NCT05009992), sponsored by the Pacific Pediatric Neuro-Oncology Consortium (PNOC). Data from the study is anticipated in CY2023.
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